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Validated and refined filtered information sources including synopses, well-conducted systematic reviews (i.e. Cochrane Reviews) and reputable practice guidelines have formed the basis for the evidence synthesis. Where filtered sources fail to address practice questions, PubMed is used to identify appropriate articles for analysis and synthesis. Extensive web searches for grey literature and unpublished resources are also used to find relevant materials referenced in PEN.

The Knowledge pathways are designed to address a topic from the broad spectrum of practice in dietetics - institutional care, primary health care, public/community health, consulting/private practice, food service management, professional education, food and the pharmaceutical industry, government.